Creatine Monohydrate

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Creatine monohydrate is one of the most extensively researched and widely used supplements in the fitness community. Gym-goers and athletes worldwide incorporate creatine into their supplement regimens to enhance performance, increase strength, and support muscle growth.


What is Creatine Monohydrate?

Creatine is a naturally occurring compound found in small amounts in certain foods and synthesized in the body from amino acids, primarily in the liver, kidneys, and pancreas. It plays a crucial role in producing adenosine triphosphate (ATP), the primary energy carrier in cells. During high-intensity exercise, ATP is rapidly consumed to fuel muscle contractions, and creatine helps replenish ATP levels, enhancing performance and delaying fatigue.

Creatine monohydrate is the most widely studied, popular, and effective form of creatine. It has been extensively studied and proven to significantly benefit athletes and fitness enthusiasts.


Enhancing Athletic Performance

One of the most compelling reasons to supplement with creatine monohydrate is its ability to improve athletic performance. Research consistently shows that creatine enhances strength, power, and endurance in high-intensity, short-duration activities such as weightlifting, sprinting, and other explosive movements.


Strength and Power

Studies have demonstrated that creatine supplementation significantly increases muscle strength and power. A meta-analysis of 22 studies involving resistance training concluded that creatine supplementation led to a 14% greater increase in strength compared to placebo. This boost in strength can translate into better gym performance, allowing you to lift heavier weights and perform more reps, ultimately leading to more significant muscle gains.


High-Intensity Exercise Performance

Creatine is particularly beneficial for high-intensity exercise. A study published in the Journal of the International Society of Sports Nutrition found that creatine supplementation improved performance in activities requiring short bursts of intense effort, such as sprinting and jumping. This improvement is attributed to creatine's role in rapidly regenerating ATP, enabling athletes to sustain maximal effort for extended periods.



While creatine is often associated with short bursts of activity, it can also benefit endurance athletes. Research indicates that creatine can enhance endurance performance by increasing muscle glycogen storage and reducing muscle damage during prolonged exercise. This can be particularly beneficial for athletes engaged in sports that require both endurance and power, such as soccer or rugby.


Supporting Muscle Growth

Muscle hypertrophy, or growth, is a primary goal for many gym-goers. Creatine monohydrate has been shown to support muscle growth through several mechanisms.


Increased Muscle Protein Synthesis

Creatine supplementation can enhance muscle protein synthesis, the process by which the body builds new muscle proteins. By increasing the availability of ATP, creatine allows for more efficient muscle contractions and recovery, leading to greater muscle protein synthesis over time. Research shows that creatine supplementation combined with resistance training results in more significant muscle mass gains than training alone.


Enhanced Cell Hydration

Creatine also promotes muscle growth by increasing intracellular water content. This phenomenon, known as cell volumization, causes muscle cells to swell, triggering anabolic signaling pathways and promoting muscle growth. The increased water content can also improve nutrient delivery to muscle cells, further supporting growth and recovery.


Reduced Muscle Breakdown

Creatine has been shown to reduce markers of muscle damage and inflammation following intense exercise. By minimizing muscle breakdown and accelerating recovery, creatine allows athletes to train more frequently and with greater intensity, increasing muscle hypertrophy.


Cognitive Benefits

In addition to its well-documented physical benefits, creatine monohydrate may positively affect cognitive function. Research suggests that creatine supplementation can enhance mental performance, particularly in tasks requiring short-term memory and quick thinking.


Improved Cognitive Function

A study published in the journal Psychopharmacology found that creatine supplementation improved cognitive performance in tasks involving memory and intelligence. This is due to creatine's role in maintaining ATP levels in the brain, ensuring adequate energy supply for cognitive processes.


Neuroprotective Effects

Creatine may also offer neuroprotective benefits, potentially reducing the risk of neurodegenerative diseases such as Alzheimer's and Parkinson's. Animal studies have shown that creatine supplementation can protect against neuronal damage and improve mitochondrial function, which is crucial for brain health.


Benefits for Aging Adults

Creatine is not only beneficial for young athletes and gym-goers but also for older adults. Muscle mass and strength naturally decline as we age, leading to a condition known as sarcopenia. Creatine supplementation, combined with resistance training, can help mitigate these effects and improve the quality of life in older adults.


Combating Sarcopenia

A study published in Medicine & Science in Sports & Exercise found that creatine supplementation significantly increased muscle mass and strength in older adults undergoing resistance training. This suggests that creatine can be an effective intervention for maintaining muscle health and functionality in aging populations.


Enhancing Daily Activities

Improving muscle strength and mass through creatine supplementation can also enhance the ability of older adults to perform daily activities. Increased muscle strength can lead to better balance, reduced risk of falls, and greater independence, which can profoundly impact the overall quality of life and longevity.


Safety and Dosage

Creatine monohydrate is widely recognized as a safe and effective supplement when used appropriately. The recommended dosage typically involves a loading phase of 20 grams per day (divided into four 5-gram doses) for 5-7 days, followed by a maintenance phase of 3-5 grams daily. This protocol helps saturate muscle creatine stores and maintain elevated levels.


Side Effects

Creatine is generally well-tolerated, with few reported side effects. The most common side effect is weight gain, primarily due to increased muscle water retention. Some individuals may experience gastrointestinal discomfort, usually mitigated by dividing the daily dose into smaller servings and taking it with food.


Long-Term Use

Long-term studies have shown that creatine supplementation is safe for extended use. Research spanning several years has found no adverse effects on kidney or liver function in healthy individuals. However, individuals with pre-existing kidney conditions should consult a healthcare professional before starting creatine supplementation.


Why Buy Creatine Monohydrate from Polokus?

Creatine monohydrate is a powerful supplement that benefits gym-goers and athletes. From enhancing strength and performance to supporting muscle growth and cognitive function, creatine is a versatile addition to any fitness regimen. Moreover, it can help older adults maintain muscle mass and improve their ability to perform daily activities.


At Polokus, we offer high-quality creatine monohydrate manufactured in an FDA-registered, cGMP-compliant, and NSF-certified facility that is rigorously tested for purity and potency. Adding Polokus creatine can help you achieve your fitness goals and enhance your overall performance.


Take your training to the next level with Polokus creatine.



Kreider, R. B., Kalman, D. S., Antonio, J., Ziegenfuss, T. N., Wildman, R., Collins, R., ... & Lopez, H. L. (2017). International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine. Journal of the International Society of Sports Nutrition, 14(1), 18.


Mielgo-Ayuso, J., Calleja-González, J., Marqués-Jiménez, D., Caballero-García, A., Córdova, A., & Fernández-Lázaro, D. (2019). Effect of creatine supplementation on athletic performance in soccer players: a systematic review and meta-analysis. Nutrients, 11(4), 757.


Candow, D. G., Vogt, E., Johannsmeyer, S., Forbes, S. C., & Farthing, J. P. (2015). Strategic creatine supplementation and resistance training in healthy older adults. Applied Physiology, Nutrition, and Metabolism, 40(7), 689-694.,improve%20activities%20of%20daily%20living


Dolan, E., Swinton, P. A., Pain, M. T., & Tufano, J. J. (2019). The role of agonist–antagonist muscle coactivation during fatiguing repetitive maximal isokinetic knee flexion and extension exercise. Journal of Strength and Conditioning Research, 33(9), 2324-2332.


**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.